Chen will present his work on derivation of trophoblast stem cells from naïve human pluripotent stem cells in the concurrent session on Early Development and Pluripotency at the ISSCR 2020 Virtual Meeting. Congrats Chen!
Laura Fischer, a second-year Ph.D. student in the Theunissen lab, has received an honorable mention from the National Science Foundation’s (NSF) 2020 Graduate Research Fellowship Program (GRFP).
The program recognizes and supports outstanding graduate students in NSF-supported science, technology, engineering, and mathematics disciplines who are pursuing research-based master’s and doctoral degrees at accredited United States institutions.
Kudos to Laura. We’re looking forward to your exciting studies!
We’re excited to welcome our newest lab member: Dr. Rowan Karvas, who completed her graduate work with Professor Michael Roberts and Dr. Laura Schulz at the University of Missouri. Please see our Team page for more information.
Our paper examining the trophoblast potential of distinct human stem cell states was published today in eLife. We report that naive, but not primed, human pluripotent stem cells (hPSC) can directly differentiate into trophoblast stem cells (TSC). The derivation of TSCs from naïve hPSCs presents a new model system to elucidate early mechanisms governing placental development and associated pathologies. This study was a collaboration with the Solnica-Krezel, Wang and Kommagani labs at Washington University.
Image of naive hPSC-derived human TSCs stained with a KRT7 antibody by Chen Dong (Theunissen Lab).
Thor Theunissen was awarded an NIH Director’s New Innovator Award. The award supports unusually innovative research from early-career investigators who are within 10 years of their final degrees or clinical residencies. See the press release related to this award here.